Calpain 2 Polyclonal Antibody
- SKU:
- CAB2671
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Calpain 2 Polyclonal Antibody |
| Product Code: | CAB2671 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, Mouse brain, Mouse skin |
| Cellular Location: | Cell membrane, Cytoplasm |
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human Calpain 2 (NP_001739.2). |
| Sequence: | LEEFD ISEDD IDDGF RRLFA QLAGE DAEIS AFELQ TILRR VLAKR QDIKS DGFSI ETCKI MVDML DSDGS GKLGL KEFYI LWTKI QKYQK IYREI DVDRS GTMNS YEMRK ALEEA GFKMP CQLHQ VIVAR FADDQ LIIDF DNFVR CLVRL ETLFK IFKQL DPENT GTIEL DLISW LCFSV L |
| Synonyms: | CANP2, mCANP, CANPL2, CANPml |
| Calculated MW: | 80kDa |
| Observed MW: | 80kDa |
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