Calpain 1 Polyclonal Antibody
- SKU:
- CAB21673
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Calpain 1 Polyclonal Antibody |
| Product Code: | CAB21673 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Cytoplasm |
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-330 of human Calpain 1 (NP_005177.2). |
| Sequence: | KQRAR ELGLG RHENA IKYLG QDYEQ LRVRC LQSGT LFRDE AFPPV PQSLG YKDLG PNSSK TYGIK WKRPT ELLSN PQFIV DGATR TDICQ GALGD CWLLA AIASL TLNDT LLHRV VPHGQ SFQNG YAGIF HFQLW QFGEW VDVVV DDLLP IKDGK LVFVH SAEGN EFWSA LLEKA YAKVN GSYEA LSGGS TSEGF EDFTG GVTEW YELRK APSDL YQIIL KALER GSLLG CSIDI SSVLD MEAIT FKKLV KGHAY SVTGA KQVNY RGQVV SLIRM RNPWG EVEWT GAWSD SSSEW NNVDP YERDQ LRVKM E |
| Synonyms: | CANP, muCL, CANP1, SPG76, CANPL1, muCANP |
| Calculated MW: | 82kDa |
| Observed MW: | Refer to figures |
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