Antibody Name:	CALCA Antibody (PACO07322)
Antibody SKU:	PACO07322
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:10000-1:20000, WB:1:500-1:2000
Species Reactivity:	Human
Immunogen:	Synthetic peptide from human protein at AA range: 80-141

Form:	Liquid
Storage Buffer:	PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method:	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot analysis of Jurkat U937 Raji mouse-eye lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000.

Synonyms:

Calcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide) (CCP) (PDN-21)]

UniProt Protein Function:	CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11p15.2 Cellular Component: extracellular region; extracellular space Molecular Function:calcitonin receptor binding; identical protein binding; protein binding Biological Process: activation of protein kinase activity; cellular protein metabolic process; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); embryo implantation; monocyte chemotaxis; negative regulation of bone resorption; negative regulation of transcription, DNA-dependent; positive regulation of adenylate cyclase activity
NCBI Summary:	This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
UniProt Code:	P01258
NCBI GenInfo Identifier:	322510018
NCBI Gene ID:	796
NCBI Accession:	P01258.2
UniProt Secondary Accession:	P01258,Q13935, Q13937, Q52LX7, B7ZL39,
UniProt Related Accession:	P01258,P06881
Molecular Weight:	38.6kDa
NCBI Full Name:	Calcitonin
NCBI Synonym Full Names:	calcitonin related polypeptide alpha
NCBI Official Symbol:	CALCA
NCBI Official Synonym Symbols:	CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
NCBI Protein Information:	calcitonin; calcitonin gene-related peptide 1
UniProt Protein Name:	Calcitonin
UniProt Synonym Protein Names:	CalcitoninKatacalcinAlternative name(s):Calcitonin carboxyl-terminal peptide; CCP
UniProt Gene Name:	CALCA