CADM4 Antibody (PACO19380)
- SKU:
- PACO19380
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CADM4 Antibody (PACO19380) |
| Antibody SKU: | PACO19380 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human CADM4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO19380(CADM4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: RAW264.7 cells, mouse brain tissue, Primary antibody: PACO19380(CADM4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19380(CADM4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | IGSF4C (immunoglobulin superfamily member 4C), also known as CADM4 (cell adhesion molecule 4), NECL4 or TSLL2, is a 388 amino acid, single-pass type I membrane protein that contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed in kidney, brain and prostate, IGSF4C exists as both a monomer and a homodimer and is thought to be involved in cell-cell adhesion, possibly playing a role in tumor suppression. Human IGSF4C shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding IGSF4C maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs) |
| Synonyms: | cell adhesion molecule 4 |
| UniProt Protein Function: | Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NFZ8 |
| NCBI GenInfo Identifier: | 21686977 |
| NCBI Gene ID: | 199731 |
| NCBI Accession: | NP_660339.1 |
| UniProt Secondary Accession: | Q8NFZ8,Q9Y4A4, B2R7L5 |
| UniProt Related Accession: | Q8NFZ8 |
| Molecular Weight: | 42,785 Da |
| NCBI Full Name: | cell adhesion molecule 4 |
| NCBI Synonym Full Names: | cell adhesion molecule 4 |
| NCBI Official Symbol: | CADM4 |
| NCBI Official Synonym Symbols: | NECL4; TSLL2; IGSF4C; Necl-4; synCAM4 |
| NCBI Protein Information: | cell adhesion molecule 4 |
| UniProt Protein Name: | Cell adhesion molecule 4 |
| UniProt Synonym Protein Names: | Immunoglobulin superfamily member 4C; IgSF4C; Nectin-like protein 4; NECL-4; TSLC1-like protein 2 |
| Protein Family: | Cell adhesion molecule |
| UniProt Gene Name: | CADM4 |
| UniProt Entry Name: |
| Antibodies |
| CADM4 Antibody (PACO02634) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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