CACTIN Antibody (PACO07291)
- SKU:
- PACO07291
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CACTIN Antibody (PACO07291) |
| Antibody SKU: | PACO07291 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:10000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide from human protein at AA range: 141-190 |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of hepg2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000. |
| Synonyms: | CACTIN C19orf29 |
| UniProt Protein Function: | CACTIN: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing. Belongs to the CACTIN family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Spliceosome; RNA splicingChromosomal Location of Human Ortholog: 19p13.3Cellular Component: nucleoplasm; cytoplasm; nucleusMolecular Function: protein bindingBiological Process: nuclear mRNA splicing, via spliceosome; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein amino acid phosphorylation; inhibition of NF-kappaB transcription factor; multicellular organismal development; negative regulation of toll-like receptor signaling pathway; negative regulation of interleukin-8 production; innate immune response; negative regulation of tumor necrosis factor production; negative regulation of interferon-beta production |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WUQ7 |
| NCBI GenInfo Identifier: | 122937392 |
| NCBI Gene ID: | 58509 |
| NCBI Accession: | NP_001074012.1 |
| UniProt Secondary Accession: | Q8WUQ7 |
| UniProt Related Accession: | Q8WUQ7 |
| Molecular Weight: | 89 kDa |
| NCBI Full Name: | cactin |
| NCBI Synonym Full Names: | cactin, spliceosome C complex subunit |
| NCBI Official Symbol: | CACTIN |
| NCBI Official Synonym Symbols: | fSAPc; C19orf29; NY-REN-24 |
| NCBI Protein Information: | cactin |
| UniProt Protein Name: | Cactin |
| UniProt Synonym Protein Names: | Renal carcinoma antigen NY-REN-24 |
| Protein Family: | Cactin |
| UniProt Gene Name: | CACTIN |
| UniProt Entry Name: | CATIN_HUMAN |
Related Products
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos
ompF Antibody
Overview Product Name:ompF AntibodyProduct Code:PACO64865Size:50µLTarget Names:ompFSpecies Reactivity:Escherichia coli
Hmgb1 Antibody
Overview Product Name:Hmgb1 AntibodyProduct Code:PACO64769Size:50µLTarget Names:Hmgb1Species Reactivity:RatHost
RIMS4 Antibody
Overview Product Name:RIMS4 AntibodyProduct Code:PACO64925Size:50µLTarget Names:RIMS4Species Reactivity:HumanHos
C22orf39 Antibody
Overview Product Name:C22orf39 AntibodyProduct Code:PACO64621Size:50µLTarget Names:C22orf39Species Reactivity:Human<