CACNG6 Antibody (PACO63915)
- SKU:
- PACO63915
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CACNG6 Antibody (PACO63915) |
| Antibody SKU: | PACO63915 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Voltage-dependent calcium channel gamma-6 subunit protein (22-39AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of A549 cells with PACO63915 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Synonyms: | Voltage-dependent calcium channel gamma-6 subunit (Neuronal voltage-gated calcium channel gamma-6 subunit), CACNG6 |
| UniProt Protein Function: | CACNG6: Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 19q13.4Cellular Component: plasma membrane |
| UniProt Protein Details: | |
| NCBI Summary: | Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q9BXT2 |
| NCBI GenInfo Identifier: | 20532019 |
| NCBI Gene ID: | 59285 |
| NCBI Accession: | Q9BXT2.1 |
| UniProt Secondary Accession: | Q9BXT2 |
| UniProt Related Accession: | Q9BXT2 |
| Molecular Weight: | 28,129 Da |
| NCBI Full Name: | Voltage-dependent calcium channel gamma-6 subunit |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 6 |
| NCBI Official Symbol: | CACNG6 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | voltage-dependent calcium channel gamma-6 subunit |
| UniProt Protein Name: | Voltage-dependent calcium channel gamma-6 subunit |
| UniProt Synonym Protein Names: | Neuronal voltage-gated calcium channel gamma-6 subunit |
| Protein Family: | Voltage-dependent calcium channel |
| UniProt Gene Name: | CACNG6 |
| UniProt Entry Name: | CCG6_HUMAN |
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