CACNG3 Antibody (PACO07022)
- SKU:
- PACO07022
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CACNG3 Antibody (PACO07022) |
| Antibody SKU: | PACO07022 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | WB, IHC |
| Recommended Dilutions: | WB:1:1000-1:2000, IHC:1:200-1:500 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic Peptide |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | Affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using CACNG3 Polyclonal Antibody. |
 | Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNG3 Polyclonal Antibody. |
| Synonyms: | Voltage-dependent calcium channel γ-3 subunit |
| UniProt Protein Function: | CACNG3: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.Protein type: Membrane protein, multi-pass; Channel, calcium; Membrane protein, integralChromosomal Location of Human Ortholog: 16p12.1Cellular Component: plasma membraneMolecular Function: channel regulator activity; voltage-gated calcium channel activityBiological Process: transmission of nerve impulse |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood absence epilepsy. [provided by RefSeq, Dec 2010] |
| UniProt Code: | O60359 |
| NCBI GenInfo Identifier: | 6685277 |
| NCBI Gene ID: | 10368 |
| NCBI Accession: | O60359.1 |
| UniProt Secondary Accession: | O60359 |
| UniProt Related Accession: | O60359 |
| Molecular Weight: | 35,549 Da |
| NCBI Full Name: | Voltage-dependent calcium channel gamma-3 subunit |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 3 |
| NCBI Official Symbol: | CACNG3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | voltage-dependent calcium channel gamma-3 subunit |
| UniProt Protein Name: | Voltage-dependent calcium channel gamma-3 subunit |
| UniProt Synonym Protein Names: | Neuronal voltage-gated calcium channel gamma-3 subunit; Transmembrane AMPAR regulatory protein gamma-3; TARP gamma-3 |
| Protein Family: | Voltage-dependent calcium channel |
| UniProt Gene Name: | CACNG3 |
| UniProt Entry Name: | CCG3_HUMAN |
| Antibodies |
| CACNG3 Antibody (PACO08136) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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