c-myc Monoclonal Antibody [NYRhc-myc] (CPAB0484)

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SKU:
CPAB0484
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
NYRhc-myc

Description

system_update_alt Datasheet
Product Name:c-myc Antibody
Product Sku:CPAB0484
Size:500μg
Host Species:mouse
Immunogen:Synthetic peptides
Clone:NYRhc-myc.
Reactivity:Other bodies
Applications:
Purification Method:Protein A
Isotype:IgG1
Background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms:MYC, CMYC, C-MYS, V-MYC, P64.
Storage Buffer:Antibody is shipped lyophilized at ambient temperature.
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