c-Fos Polyclonal Antibody
- SKU:
- CAB21419
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | c-Fos Polyclonal Antibody |
| Product Code: | CAB21419 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human c-Fos (NP_005243.1). |
| Sequence: | MMFSG FNADY EASSS RCSSA SPAGD SLSYY HSPAD SFSSM GSPVN AQDFC TDLAV SSANF IPTVT AISTS PDLQW LVQPA LVSSV APSQT RAPHP FGVPA PSAGA YSRAG VVKT |
| Synonyms: | p55, AP-1, C-FOS |
| Calculated MW: | 41kDa |
| Observed MW: | 55-60kDa |
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