Description
Product Name: | c-Fos Monoclonal Antibody |
Product Code: | CAB24620 |
Reactivity: | Human |
Applications: | Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC63309 |
Reactivity: | Human |
Tested Applications: | IHC-P, IF/ICC, ELISA |
Key Applications: | Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 211-281 of human c-Fos(NP_005243.1). |
Sequence: | GFPEE MSVAS LDLTG GLPEV ATPES EEAFT LPLLN DPEPK PSVEP VKSIS SMELK TEPFD DFLFP ASSRP S |
Synonyms: | p55, AP-1, C-FOS |
Calculated MW: | 41kDa |
Observed MW: | Refer to figures |