BTN2A2 Antibody (PACO15893)
- SKU:
- PACO15893
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BTN2A2 Antibody (PACO15893) |
| Antibody SKU: | PACO15893 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human BTN2A2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15893(BTN2A2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid, and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Synonyms: | butyrophilin, subfamily 2, member A2 |
| UniProt Protein Function: | BTN2A2: Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. Belongs to the immunoglobulin superfamily. BTN/MOG family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p22.2Cellular Component: plasma membraneMolecular Function: protein bindingBiological Process: negative regulation of activated T cell proliferation; negative regulation of cellular metabolic process; negative regulation of cytokine secretion |
| UniProt Protein Details: | |
| NCBI Summary: | Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| UniProt Code: | Q8WVV5 |
| NCBI GenInfo Identifier: | 308522746 |
| NCBI Gene ID: | 10385 |
| NCBI Accession: | NP_001184166.1 |
| UniProt Secondary Accession: | Q8WVV5,O00480, A6NM84, B4DE97, B4DQ01, E9PH07 |
| UniProt Related Accession: | Q8WVV5 |
| Molecular Weight: | 41.7kD |
| NCBI Full Name: | butyrophilin subfamily 2 member A2 isoform a |
| NCBI Synonym Full Names: | butyrophilin subfamily 2 member A2 |
| NCBI Official Symbol: | BTN2A2 |
| NCBI Official Synonym Symbols: | BTF2; BT2.2; BTN2.2 |
| NCBI Protein Information: | butyrophilin subfamily 2 member A2 |
| UniProt Protein Name: | Butyrophilin subfamily 2 member A2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Butyrophilin subfamily |
| UniProt Gene Name: | BTN2A2 |
| UniProt Entry Name: |
| Antibodies |
| BTN2A2 Antibody (PACO08061) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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