BRWD1 Antibody (PACO20873)
- SKU:
- PACO20873
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BRWD1 Antibody (PACO20873) |
| Antibody SKU: | PACO20873 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human BRWD1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20873(BRWD1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acid, typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex. |
| Synonyms: | bromodomain and WD repeat domain containing 1 |
| UniProt Protein Function: | May be a transcriptional activator. May be involved in chromatin remodeling. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011] |
| UniProt Code: | Q9NSI6 |
| NCBI GenInfo Identifier: | 313104296 |
| NCBI Gene ID: | 54014 |
| NCBI Accession: | Q9NSI6.4 |
| UniProt Secondary Accession: | Q9NSI6,O43721, Q5R2V0, Q5R2V1, Q6P2D1, Q8TCV3, Q96QG9 Q96QH0, Q9NUK1, C9JK25, |
| UniProt Related Accession: | Q9NSI6 |
| Molecular Weight: | 263kDa |
| NCBI Full Name: | Bromodomain and WD repeat-containing protein 1 |
| NCBI Synonym Full Names: | bromodomain and WD repeat domain containing 1 |
| NCBI Official Symbol: | BRWD1 |
| NCBI Official Synonym Symbols: | N143; WDR9; DCAF19; C21orf107 |
| NCBI Protein Information: | bromodomain and WD repeat-containing protein 1 |
| UniProt Protein Name: | Bromodomain and WD repeat-containing protein 1 |
| UniProt Synonym Protein Names: | WD repeat-containing protein 9 |
| Protein Family: | Bromodomain and WD repeat-containing protein |
| UniProt Gene Name: | BRWD1 |
| Antibodies |
| Anti-BRWD1 Antibody (CAB12656) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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