Description
| Product Name: | BRD7 Polyclonal Antibody |
| Product Code: | CAB23265 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, U266, Mouse brain, Rat liver |
| Cellular Location: | Nucleus |
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human BRD7. (NP_037395.2). |
| Sequence: | MGKKH KKHKS DKHLY EEYVE KPLKL VLKVG GNEVT ELSTG SSGHD SSLFE DKNDH DKHKD RKRKK RKKGE KQIPG EEKGR KRRRV KEDKK KRDRD |
| Synonyms: | BP75, NAG4, CELTIX1, SMARCI1 |
| Calculated MW: | 74kDa |
| Observed MW: | 75kDa |