BRD2 Monoclonal Antibody
- SKU:
- CAB23166
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | BRD2 Monoclonal Antibody |
| Product Code: | CAB23166 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56992 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, HeLa, MCF7, RAW 264.7 |
| Cellular Location: | Nucleus |
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-345 of human BRD2 (NP_005095.1). |
| Sequence: | MLQNV TPHNK LPGEG NAGLL GLGPE AAAPG KRIRK PSLLY EGFES PTMAS VPALQ LTPAN PPPPE VSNPK KPGRV TNQLQ YLHKV VMKAL WKHQF AWPFR QPVDA VKLGL PDYHK IIKQP MDMGT IKRRL ENNYY WAASE CMQDF NTMFT NCYIY NKPTD DIVLM AQTLE KIFLQ KVASM PQEEQ ELVVT IPKNS HKKGA KLAAL QGSVT SAHQV PAVSS VSHTA LYTPP PEIPT TVLNI PHPSV ISSPL LKSLH SAGPP LLAVT AAPPA QPLAK KKGVK RKADT TTPTP TAILA PGSPA SPPGS LEPKA ARLPP MRRES GRPIK PPRKD LPDSQ QQHQS SKKGK |
| Synonyms: | FSH, NAT, RNF3, FSRG1, RING3, FSHRG1, D6S113E, O27.1.1, BRD2-IT1 |
| Calculated MW: | 88kDa |
| Observed MW: | 112kDa |
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