BPHL Antibody (PACO08037)
- SKU:
- PACO08037
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BPHL Antibody (PACO08037) |
| Antibody SKU: | PACO08037 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human BPHL |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | biphenyl hydrolase-like (serine hydrolase);BPHL;BPH-RP;MCNAA;MGC125930;MGC41865;VACVASE ; |
| UniProt Protein Function: | BPHL: Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. Belongs to the AB hydrolase superfamily. Lipase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.1.-.-; HydrolaseChromosomal Location of Human Ortholog: 6p25Cellular Component: mitochondrial outer membrane; mitochondrionMolecular Function: alpha-amino-acid esterase activity; hydrolase activityBiological Process: amino acid metabolic process; response to toxin; xenobiotic metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009] |
| UniProt Code: | Q86WA6 |
| NCBI GenInfo Identifier: | 39931107 |
| NCBI Gene ID: | 670 |
| NCBI Accession: | Q86WA6.1 |
| UniProt Secondary Accession: | Q86WA6,Q00306, Q13855, Q3KP51 |
| UniProt Related Accession: | Q86WA6 |
| Molecular Weight: | 31,107 Da |
| NCBI Full Name: | Valacyclovir hydrolase |
| NCBI Synonym Full Names: | biphenyl hydrolase like |
| NCBI Official Symbol: | BPHL |
| NCBI Official Synonym Symbols: | MCNAA; BPH-RP; VACVASE |
| NCBI Protein Information: | valacyclovir hydrolase |
| UniProt Protein Name: | Valacyclovir hydrolase |
| UniProt Synonym Protein Names: | Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; Breast epithelial mucin-associated antigen; MCNAA |
| Protein Family: | Valacyclovir hydrolase |
| UniProt Gene Name: | BPHL |
| UniProt Entry Name: | BPHL_HUMAN |
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