Bovine DNase Recombinant Protein (RPPB1526)

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SKU:
RPPB1526
Product Type:
Recombinant Protein
Species:
Bovine
Uniprot:
P00639

Description

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Product Name:Bovine DNase Recombinant Protein
Product Code:RPPB1526
Size:100mg
Species:Bovine
Target:DNase
Synonyms:EC 3.1.21.1, Deoxyribonuclease I, DNase I, DNL1, DRNI, FLJ38093, DNASE1, Deoxyribonuclease-1.
Source:Extracted from Pancreas
Physical Appearance:Sterile lyophilized freezed dried powder.

Deoxyribonuclease I Bovine (bDNase), an enzyme which selectively cleaves DNA. Bovine Dnase is an endonuclease enzyme which splits phosphodiester linkages within polynucleotides, acting primarely on single stranded DNA (ssDNA), double stranded DNA (ddDNA) and chromatin. Dnase is activated by bivalent metals such as Mg+2 and Ca+2 .Dnase enzymes are common reagents used in biochemical methods requiring diestion of DNA and recovery of RNA, or where DNA is to be removed without affecting structural proteins or enzymes. Dnase enzymes are also used in tissue culture to digest DNA from damaged cells, resulting in reduced viscosity, and for removal of membrane-bound DNA fragments.

UniProt Protein Function:Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:P00639
NCBI GenInfo Identifier:27806969
NCBI Gene ID:282217
NCBI Accession:NP_776959.1
UniProt Secondary Accession:P00639,Q8MJ27, A5PK44
UniProt Related Accession:P00639
Molecular Weight:
NCBI Full Name:deoxyribonuclease-1
NCBI Synonym Full Names:deoxyribonuclease I
NCBI Official Symbol:DNASE1��
NCBI Official Synonym Symbols:
NCBI Protein Information:deoxyribonuclease-1; DNase I
UniProt Protein Name:Deoxyribonuclease-1
UniProt Synonym Protein Names:Deoxyribonuclease I; DNase I
Protein Family:
UniProt Gene Name:DNASE1��
UniProt Entry Name:DNAS1_BOVIN
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