Description
Antibody Name: | Botulinum neurotoxin type C1 Antibody (PACO34322) |
Antibody SKU: | PACO34322 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Clostridium botulinum |
Immunogen: | Recombinant Clostridium botulinum Botulinum neurotoxin type C1 protein (2-428AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves syntaxin. |
Synonyms: | Botulinum neurotoxin type C1 (BoNT/C1) (EC 3.4.24.69) (Bontoxilysin-C1) [Cleaved into: Botulinum neurotoxin C1 light chain; Botulinum neurotoxin C1 heavy chain] |
UniProt Protein Function: | Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves syntaxin. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P18640 |
NCBI GenInfo Identifier: | 115185 |
NCBI Gene ID: | |
NCBI Accession: | P18640.2 |
UniProt Secondary Accession: | P18640 |
UniProt Related Accession: | P18640 |
Molecular Weight: | 64.87kD |
NCBI Full Name: | Botulinum neurotoxin type C1 |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | Botulinum neurotoxin type C1 |
UniProt Synonym Protein Names: | Bontoxilysin-C1 |
Protein Family: | Botulinum neurotoxin |
UniProt Gene Name: | BoNT/C1 |
UniProt Entry Name: |