BOLL Polyclonal Antibody
- SKU:
- CAB8255
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | BOLL Polyclonal Antibody |
| Product Code: | CAB8255 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse testis, Rat testis |
| Cellular Location: | Cytoplasm |
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human BOLL (NP_149019.1). |
| Sequence: | MQTDS LSPSP NPVSP VPLNN PTSAP RYGTV IPNRI FVGGI DFKTN ESDLR KFFSQ YGSVK EVKIV NDRAG VSKGY GFVTF ETQED AQKIL QEAEK LNYKD KKLNI GPAIR KQQVG IPRSS IMPAA GTMYL TTSTG YPYTY HNGVA YFHTP EVTSV PPPWP SRSVC SSPVM VAQPI YQQPA YHYQA TTQYL PGQWQ WSVPQ PSASS APFLY LQPSE VIYQP VEIAQ DGGCV PPPLS LMETS VPEPY SDHGV QATYH QVYAP SAITM PAPVM QPEPI KTVWS IHY |
| Synonyms: | BOULE |
| Calculated MW: | 31kDa |
| Observed MW: | 35-42kDa |
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