Description
Product Name: | BNIP3L Monoclonal Antibody |
Product Code: | CAB24803 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC64186 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | PC-12, MCF7 |
Cellular Location: | Endoplasmic reticulum, Membrane, Mitochondrion outer membrane, Nucleus envelope, Single-pass membrane protein |
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c.
Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 1-187 of human BNIP3L(NP_004322.1). |
Sequence: | MSSHL VEPPP PLHNN NNNCE ENEQS LPPPA GLNSS WVELP MNSSN GNDNG NGKNG GLEHV PSSSS IHNGD MEKIL LDAQH ESGQS SSRGS SHCDS PSPQE DGQIM FDVEM HTSRD HSSQS EEEVV EGEKE VEALK KSADW VSDWS SRPEN IPPKE FHFRH PKRSV SLSMR KSGAM KKGGI FSAEF LK |
Synonyms: | NIX, BNIP3a |
Calculated MW: | 24kDa |
Observed MW: | 38kDa |