| UniProt Protein Function: | BMP8B: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Belongs to the TGF-beta family.Protein type: Secreted; Secreted, signal peptide; CytokineChromosomal Location of Human Ortholog: 1p35-p32Cellular Component: extracellular spaceMolecular Function: cytokine activity; growth factor activity; transforming growth factor beta receptor bindingBiological Process: BMP signaling pathway; cartilage development; cell development; growth; ossification; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P34820 |
| NCBI GenInfo Identifier: | 7018292 |
| NCBI Gene ID: | |
| NCBI Accession: | CAB75681 |
| UniProt Secondary Accession: | P34820,Q32NE5, Q53ZM7, Q9NUF0, E7EMY8 |
| UniProt Related Accession: | P34820 |
| Molecular Weight: | 39,151 Da |
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| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
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| NCBI Protein Information: | |
| UniProt Protein Name: | Bone morphogenetic protein 8B |
| UniProt Synonym Protein Names: | Osteogenic protein 2; OP-2 |
| Protein Family: | |
| UniProt Gene Name: | BMP8B |
| UniProt Entry Name: | BMP8B_HUMAN |
