Name: Biotin Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU: AGEL3324
Availability: OutOfStock

Biotin Anti-Human CD127/IL-7RA Antibody [A019D5]

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SKU:

AGEL3324

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OverviewProduct Name:GenieFluor 488 Anti-Human CD127/IL-7RA Antibody [A019D5]Product Code:AGEL2278Clone No:A019D5Synonyms:Interle

OverviewProduct Name:PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody [A019D5]Product Code:AGEL2276Clone No:A019D5Synonyms:Interleuki

OverviewProduct Name:PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody [A019D5]Product Code:AGEL3151Clone No:A019D5Synonyms:Interleu

OverviewProduct Name:GenieFluor 647 Anti-Human CD127/IL-7RA Antibody [A019D5]Product Code:AGEL2279Clone No:A019D5Synonyms:Interle

OverviewProduct Name:PerCP/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody [A019D5]Product Code:AGEL2277Clone No:A019D5Synonyms:Inter

Isotype:	Mouse IgG1, κ
Isotype Control:	Biotin Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:	Biotin
Applications:	FCM
Recommended Dilution:	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:	Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.

Shipping:	Biological ice pack at 4°C
Form:	Liquid
Gene ID:	3575
Swissprot:	P16871
Background Information:	CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.