Biotin Anti-Human CD123 Antibody [6H6]
- SKU:
- AGEL3259
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, k
- Clone:
- 6H6
- Conjugation:
- Biotin
Description
Product Name: | Biotin Anti-Human CD123 Antibody [6H6] |
Product Code: | AGEL3259 |
Size: | 25ug, 100ug |
Clone No: | 6H6 |
Synonyms: | IL-3Rα, IL-3 Receptor alpha |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | Biotin Mouse IgG1, κ Isotype Control [MOPC-21] |
Conjugation: | Biotin |
Applications: | FCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Swissprot: | P26951 |
Background Information: | CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |