Description
| Antibody Name: | Bglap Antibody (PACO25252) |
| Antibody SKU: | PACO25252 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Osteocalcin protein (50-99AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. |
| Synonyms: | Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid, containing protein), Bglap, Bglap2 |
| UniProt Protein Function: | osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q34 Cellular Component: cell projection; cytoplasm; dendrite; extracellular region; extracellular space; Golgi apparatus; perikaryon; rough endoplasmic reticulum; vesicle Molecular Function:calcium ion binding; structural constituent of bone Biological Process: aging; biomineral formation; cell aging; odontogenesis; ossification; osteoblast development; osteoblast differentiation; regulation of bone mineralization; response to activity; response to drug; response to estrogen; response to ethanol; response to glucocorticoid stimulus; response to gravity; response to hydroxyisoflavone; response to inorganic substance; response to mechanical stimulus; response to nutrient levels; response to organic cyclic compound; response to testosterone stimulus; response to vitamin D; response to vitamin K; response to zinc ion |
| NCBI Summary: | highly conserved protein associated with mineralized bone matrix; protein is secreted by calcified tissues and is regulated by vitamin D3 [RGD, Feb 2006] |
| UniProt Code: | P04640 |
| NCBI GenInfo Identifier: | 11761543 |
| NCBI Gene ID: | 25295 |
| NCBI Accession: | NP_038200.1 |
| UniProt Related Accession: | P04640 |
| Molecular Weight: | 10,927 Da |
| NCBI Full Name: | osteocalcin preproprotein |
| NCBI Synonym Full Names: | bone gamma-carboxyglutamate protein |
| NCBI Official Symbol: | Bglap |
| NCBI Official Synonym Symbols: | Bgp; Bgpr; Bgpra; Bglap2 |
| NCBI Protein Information: | osteocalcin |
| UniProt Protein Name: | Osteocalcin |
| UniProt Synonym Protein Names: | Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein |
| UniProt Gene Name: | Bglap |