Description
Antibody Name: | Bglap Antibody (PACO25252) |
Antibody SKU: | PACO25252 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Rat |
Immunogen: | Recombinant Rat Osteocalcin protein (50-99AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. |
Synonyms: | Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid, containing protein), Bglap, Bglap2 |
UniProt Protein Function: | osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q34 Cellular Component: cell projection; cytoplasm; dendrite; extracellular region; extracellular space; Golgi apparatus; perikaryon; rough endoplasmic reticulum; vesicle Molecular Function:calcium ion binding; structural constituent of bone Biological Process: aging; biomineral formation; cell aging; odontogenesis; ossification; osteoblast development; osteoblast differentiation; regulation of bone mineralization; response to activity; response to drug; response to estrogen; response to ethanol; response to glucocorticoid stimulus; response to gravity; response to hydroxyisoflavone; response to inorganic substance; response to mechanical stimulus; response to nutrient levels; response to organic cyclic compound; response to testosterone stimulus; response to vitamin D; response to vitamin K; response to zinc ion |
NCBI Summary: | highly conserved protein associated with mineralized bone matrix; protein is secreted by calcified tissues and is regulated by vitamin D3 [RGD, Feb 2006] |
UniProt Code: | P04640 |
NCBI GenInfo Identifier: | 11761543 |
NCBI Gene ID: | 25295 |
NCBI Accession: | NP_038200.1 |
UniProt Related Accession: | P04640 |
Molecular Weight: | 10,927 Da |
NCBI Full Name: | osteocalcin preproprotein |
NCBI Synonym Full Names: | bone gamma-carboxyglutamate protein |
NCBI Official Symbol: | Bglap |
NCBI Official Synonym Symbols: | Bgp; Bgpr; Bgpra; Bglap2 |
NCBI Protein Information: | osteocalcin |
UniProt Protein Name: | Osteocalcin |
UniProt Synonym Protein Names: | Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein |
UniProt Gene Name: | Bglap |