Description
| Antibody Name: | Bglap Antibody (PACO25252) | 
| Antibody SKU: | PACO25252 | 
| Size: | 50ug | 
| Host Species: | Rabbit | 
| Tested Applications: | ELISA | 
| Recommended Dilutions: | |
| Species Reactivity: | Rat | 
| Immunogen: | Recombinant Rat Osteocalcin protein (50-99AA) | 
| Form: | Liquid | 
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | 
| Purification Method: | >95%, Protein G purified | 
| Clonality: | Polyclonal | 
| Isotype: | IgG | 
| Conjugate: | Non-conjugated | 
| Background: | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. | 
| Synonyms: | Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid, containing protein), Bglap, Bglap2 | 
| UniProt Protein Function: | osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family. | 
| UniProt Protein Details: | Protein type:Cell development/differentiation; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q34 Cellular Component: cell projection; cytoplasm; dendrite; extracellular region; extracellular space; Golgi apparatus; perikaryon; rough endoplasmic reticulum; vesicle Molecular Function:calcium ion binding; structural constituent of bone Biological Process: aging; biomineral formation; cell aging; odontogenesis; ossification; osteoblast development; osteoblast differentiation; regulation of bone mineralization; response to activity; response to drug; response to estrogen; response to ethanol; response to glucocorticoid stimulus; response to gravity; response to hydroxyisoflavone; response to inorganic substance; response to mechanical stimulus; response to nutrient levels; response to organic cyclic compound; response to testosterone stimulus; response to vitamin D; response to vitamin K; response to zinc ion | 
| NCBI Summary: | highly conserved protein associated with mineralized bone matrix; protein is secreted by calcified tissues and is regulated by vitamin D3 [RGD, Feb 2006] | 
| UniProt Code: | P04640 | 
| NCBI GenInfo Identifier: | 11761543 | 
| NCBI Gene ID: | 25295 | 
| NCBI Accession: | NP_038200.1 | 
| UniProt Related Accession: | P04640 | 
| Molecular Weight: | 10,927 Da | 
| NCBI Full Name: | osteocalcin preproprotein | 
| NCBI Synonym Full Names: | bone gamma-carboxyglutamate protein | 
| NCBI Official Symbol: | Bglap | 
| NCBI Official Synonym Symbols: | Bgp; Bgpr; Bgpra; Bglap2 | 
| NCBI Protein Information: | osteocalcin | 
| UniProt Protein Name: | Osteocalcin | 
| UniProt Synonym Protein Names: | Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein | 
| UniProt Gene Name: | Bglap | 
 
 
             
             
             
             
            