BEX2 Antibody (PACO41854)
- SKU:
- PACO41854
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BEX2 Antibody (PACO41854) |
| Antibody SKU: | PACO41854 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein BEX2 protein (1-128AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO41854 at dilution of 1:100. |
 | Immunofluorescence staining of HepG2 cells with PACO41854 at 1:333, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. |
| Synonyms: | Protein BEX2 (Brain-expressed X-linked protein 2) (hBex2), BEX2 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BXY8 |
| NCBI GenInfo Identifier: | 74752443 |
| NCBI Gene ID: | |
| NCBI Accession: | |
| UniProt Secondary Accession: | Q9BXY8 |
| UniProt Related Accession: | Q9BXY8 |
| Molecular Weight: | |
| NCBI Full Name: | Protein BEX2 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Protein BEX2 |
| UniProt Synonym Protein Names: | Brain-expressed X-linked protein 2 |
| Protein Family: | Protein |
| UniProt Gene Name: | BEX2 |
| UniProt Entry Name: | BEX2_HUMAN |
| Antibodies |
| BEX2 Antibody (PACO08006) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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