BEX1 Antibody (PACO40454)
- SKU:
- PACO40454
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BEX1 Antibody (PACO40454) |
| Antibody SKU: | PACO40454 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein BEX1 protein (1-125AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO40454 at dilution of 1:100. |
| Background: | Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. |
| Synonyms: | Protein BEX1 (Brain-expressed X-linked protein 1), BEX1 |
| UniProt Protein Function: | BEX1: Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states. Belongs to the BEX family.Protein type: Cell development/differentiation; Cell cycle regulationChromosomal Location of Human Ortholog: Xq22.1|Xq22Cellular Component: transcription factor complexMolecular Function: protein bindingBiological Process: positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9HBH7 |
| NCBI GenInfo Identifier: | 91208332 |
| NCBI Gene ID: | 55859 |
| NCBI Accession: | Q9HBH7.2 |
| UniProt Secondary Accession: | Q9HBH7,Q9NZ33, A0AVN1, A8K4J3 |
| UniProt Related Accession: | Q9HBH7 |
| Molecular Weight: | 14,860 Da |
| NCBI Full Name: | Protein BEX1 |
| NCBI Synonym Full Names: | brain expressed X-linked 1 |
| NCBI Official Symbol: | BEX1 |
| NCBI Official Synonym Symbols: | BEX2; HBEX2; HGR74-h |
| NCBI Protein Information: | protein BEX1 |
| UniProt Protein Name: | Protein BEX1 |
| UniProt Synonym Protein Names: | Brain-expressed X-linked protein 1 |
| Protein Family: | Protein |
| UniProt Gene Name: | BEX1 |
| UniProt Entry Name: | BEX1_HUMAN |
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