BETVII Antibody (PACO50318)
- SKU:
- PACO50318
- Product Type:
- Antibody
- Reactivity:
- Plant
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BETVII Antibody (PACO50318) |
| Antibody SKU: | PACO50318 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Betula pendula |
| Immunogen: | Recombinant Betula pendula Profilin-1 protein (2-133AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
| Synonyms: | Profilin-1 (Allergen Bet v II) (Pollen allergen Bet v 2) (allergen Bet v 2), BETVII |
| UniProt Protein Function: | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.MiscellaneousThe variability of the residues taking part of IgE-binding epitopes might be responsible of the difference in cross-reactivity among olive pollen cultivars, and between distantly related pollen species, leading to a variable range of allergy reactions among atopic patients. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P25816 |
| NCBI GenInfo Identifier: | 130975 |
| NCBI Gene ID: | |
| NCBI Accession: | P25816.1 |
| UniProt Secondary Accession: | P25816 |
| UniProt Related Accession: | P25816 |
| Molecular Weight: | 30.11 kDa |
| NCBI Full Name: | Profilin-1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Profilin-1 |
| UniProt Synonym Protein Names: | Allergen Bet v II; Pollen allergen Bet v 2; Allergen: Bet v 2 |
| Protein Family: | |
| UniProt Gene Name: | BETVII |
| UniProt Entry Name: |
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