Beta-defensin 3/DEFB103 Recombinant Protein (RPES2705)
- SKU:
- RPES2705
- Product Type:
- Recombinant Protein
Description
Beta-defensin 3/DEFB103 Recombinant Protein
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. It is also expressed in salivary gland, bone marrow, colon, stomach, polyp and larynx. However, in small intestine, it cannot be detected. Defensin has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. Beta-defensin 3 kills multiresistant S.aureus and vancomycin-resistent E.faecium. It has no significant hemolytic activity.
| Product Name: | Beta-defensin 3/DEFB103 Recombinant Protein (RPES2705) |
| Product Code: | RPES2705 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | BD-3,DEFB-3,DEFB103,DEFB3,hBD-3,HBD3,HBP-3,HBP3 |
| Accession: | P81534 |
| Sequence: | Gly 23-Lys 67 |
| Fusion tag: | N-His |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the mature form of human DEFB103A (P81534) (Gly 23-Lys 67) was expressed, with a polyhistidine tag at the N-terminus. |
| Purity: | > 99 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 7.3 kDa |
| AP Mol Mass: | 12 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris, 0.3% Ttiton X-100, 0.3% SKL, pH 8.5 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Human Beta-defensin 5(Beta-defensin 105) ELISA Kit
Human 14-3-3 beta/YWHAB Recombinant Protein (RPES2746)
Beta-amyloid 40/Beta-APP40 Recombinant Protein (RPES1270)
Cell Death Recombinant Proteins
Beta-amyloid 42/Beta-APP42 Recombinant Protein (RPES1251)
Cell Death Recombinant Proteins