BEST2 Antibody (PACO07013)
- SKU:
- PACO07013
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | BEST2 Antibody (PACO07013) |
| Antibody SKU: | PACO07013 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | WB, IHC |
| Recommended Dilutions: | WB:1:500-1:1000, IHC:1:200-1:500 |
| Species Reactivity: | Mouse, Rat |
| Immunogen: | Synthetic Peptide |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | Affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using BEST2 Polyclonal Antibody. |
 | Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using BEST2 Polyclonal Antibody. |
| Synonyms: | Bestrophin-2 |
| UniProt Protein Function: | BEST2: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.Protein type: Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 19p13.2Cellular Component: cilium; integral to plasma membraneMolecular Function: chloride channel activityBiological Process: membrane depolarization; sensory perception of smell |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NFU1 |
| NCBI GenInfo Identifier: | 38503353 |
| NCBI Gene ID: | 54831 |
| NCBI Accession: | Q8NFU1.1 |
| UniProt Secondary Accession: | Q8NFU1,Q53YQ8, Q9NXP0 |
| UniProt Related Accession: | Q8NFU1 |
| Molecular Weight: | 57,139 Da |
| NCBI Full Name: | Bestrophin-2 |
| NCBI Synonym Full Names: | bestrophin 2 |
| NCBI Official Symbol: | BEST2 |
| NCBI Official Synonym Symbols: | VMD2L1 |
| NCBI Protein Information: | bestrophin-2 |
| UniProt Protein Name: | Bestrophin-2 |
| UniProt Synonym Protein Names: | Vitelliform macular dystrophy 2-like protein 1 |
| Protein Family: | Bestrophin |
| UniProt Gene Name: | BEST2 |
| UniProt Entry Name: | BEST2_HUMAN |
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