Beclin 1 Monoclonal Antibody (CAB21191)
- SKU:
- CAB21191
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Beclin 1 Monoclonal Antibody |
| Product Code: | CAB21191 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52856 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, Jurkat, Mouse spleen, Mouse testis, Rat lung |
| Customer Validation: | WB(Homo sapiens, Mus musculus, Mus musculus ) |
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Beclin 1 (NP_003757.1). |
| Sequence: | MEGSK TSNNS TMQVS FVCQR CSQPL KLDTS FKILD RVTIQ ELTAP LLTTA QAKPG ETQEE ETNSG EEPFI ETPRQ DGVSR RFIPP ARMMS TESAN SFTLI GEASD GGTME NLSRR LKVTG DLFDI MSGQT DVDHP LCEEC TDTLL DQLDT QLNVT ENECQ NYKRC LEILE QMNED DSEQL QMELK ELALE EERLI QELED VEKNR KIVAE NLEKV QAEAE RLDQE EAQYQ REYSE FKRQQ LELDD ELKSV ENQMR YAQTQ LDKLK KTNVF NATFH IWHSG |
| Synonyms: | ATG6, VPS30, beclin1, Beclin 1, BECN1, beclin-1 |
| Calculated MW: | 52kDa |
| Observed MW: | 60kDa |
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