Bcl-2 Polyclonal Antibody (CAB11025)
- SKU:
- CAB11025
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Bcl-2 Polyclonal Antibody |
| Product Code: | CAB11025 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse liver, Rat spleen |
| Cellular Location: | Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein |
| Customer Validation: | WB(Homo sapiens, Mus musculus, Rattus norvegicus, gallus gallus, Bos taurus)IF(Rattus norvegicus) IHC(Homo sapiens) |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-239 of human Bcl-2 (NP_000624.2). |
| Sequence: | MAHAG RTGYD NREIV MKYIH YKLSQ RGYEW DAGDV GAAPP GAAPA PGIFS SQPGH TPHPA ASRDP VARTS PLQTP AAPGA AAGPA LSPVP PVVHL TLRQA GDDFS RRYRR DFAEM SSQLH LTPFT ARGRF ATVVE ELFRD GVNWG RIVAF FEFGG VMCVE SVNRE MSPLV DNIAL WMTEY LNRHL HTWIQ DNGGW DAFVE LYGPS MRPLF DFSWL SLKTL LSLAL VGACI TLGAY LGHK |
| Synonyms: | Bcl-2, PPP1R50 |
| Calculated MW: | 26kDa |
| Observed MW: | 26kDa |
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