Bcl-2 Polyclonal Antibody (CAB0208)
- SKU:
- CAB0208
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | Bcl-2 Polyclonal Antibody |
| Product Code: | CAB0208 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein |
| Customer Validation: | WB(rat cells, HCT116, B6, MCF-7,MD-MBA-231, Rattus norvegicus, Homo sapiens, Mus musculus, Gallus gallus, Bos taurus, Sus scrofa, Giardia duodenalis, Capra hircus, Ctenopharyngodon, Ctenopharyngodon idellus, lamprey, quails, crab, Apocynum venetum leaf, hsa, Human, Cyprinus Carpio)IHC(Rattus norvegicus, Mus musculus, Homo sapiens, Oreochromis niloticus) IHC(Mus musculus)IF(Homo sapiens, Mus musculus) IHC(Gallus gallus, Mus musculus) IF(Rattus norvegicus) IP(Mus musculus, Rattus norvegicus) ICH(Mus musculus) IF(Mus musculus) RT-PCR(Homo sapiens)IP(Mouse,Rat) |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Bcl-2 (NP_000624.2). |
| Sequence: | MAHAG RTGYD NREIV MKYIH YKLSQ RGYEW DAGDV GAAPP GAAPA PGIFS SQPGH TPHPA ASRDP VARTS PLQTP AAPGA AAGPA LSPVP PVVHL TLRQA |
| Synonyms: | Bcl-2, PPP1R50 |
| Calculated MW: | 26kDa |
| Observed MW: | 26kDa |
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