Batroxobin Recombinant Protein (RPPB2990)
- SKU:
- RPPB2990
- Product Type:
- Recombinant Protein
- Uniprot:
- P04971
Description
| Product Name: | Batroxobin Recombinant Protein |
| Product Code: | RPPB2990 |
| Size: | 50µg |
| Target: | Batroxobin |
| Synonyms: | Thrombin-like enzyme batroxobin, EC 3.4.21.74, BX, Bothrops atrox serine proteinase, Venombin-A, Defibrase, Reptilase, Batroxobin. |
| Physical Appearance: | Sterile Filtered white lyophilized powder. |
| Formulation: | The Batroxobin protein was lyophilized from a concentrated (1mg/ml) solution with no additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Batroxobin in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Batroxobin although stable at room temperature for 3 weeks, should be stored below -18°C. Upon reconstitution�Batroxobin�should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| UniProt Code: | P04971 |
Batroxobin is a serin protease that reduces fibronogen levels and is originally extracted from snake venom of Bothrops Atrox. Batroxobin is used in defibrinogenation and thrombolysis and also has an effect on c-fos gene and growth factor.Batroxobin can efficiently restrain proliferation of VSMCs, by blocking the release and uptake of Ca2+, thus influencing [Ca2+]i.Batroxobin converts fibrinogen to fibrin through the restricted release of fibrinopeptide-A from fibrinogen to promote blood to clot. Unlike thrombin, it is not affected by heparin and hirudin.
Batroxobin, isolated from Bothrops atrox snake venom, has an Mw of approximately 43kDa.
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