Bag3 Antibody (PACO40618)
- SKU:
- PACO40618
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IP
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Bag3 Antibody (PACO40618) |
| Antibody SKU: | PACO40618 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IP |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IP:1:200-1:2000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse BAG family molecular chaperone regulator 3 protein (2-577AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunoprecipitating Bag3 in K562 whole cell lysate. Lane 1: Rabbit control IgG (1µg) instead of PACO40618 in K562 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000). Lane 2: PACO40618 (6µg) + K562 whole cell lysate (500µg). Lane 3: K562 whole cell lysate (10µg). |
| Background: | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. |
| Synonyms: | BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis), Bag3, Bis |
| UniProt Protein Function: | Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.Subunit structure: Binds to the ATPase domain of HSP/HSC70 chaperones. Binds to Bcl-2 and PLC-gamma By similarity. Interacts with DNAJB6 By similarity.Sequence similarities: Contains 1 BAG domain.Contains 2 WW domains. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9JLV1 |
| NCBI GenInfo Identifier: | 341940275 |
| NCBI Gene ID: | 29810 |
| NCBI Accession: | Q9JLV1.2 |
| UniProt Secondary Accession: | Q9JLV1,Q9CQL3, Q9JJC7 |
| UniProt Related Accession: | Q9JLV1 |
| Molecular Weight: | 61,860 Da |
| NCBI Full Name: | BAG family molecular chaperone regulator 3 |
| NCBI Synonym Full Names: | BCL2-associated athanogene 3 |
| NCBI Official Symbol: | Bag3 |
| NCBI Official Synonym Symbols: | Bis; mg638; AA407278 |
| NCBI Protein Information: | BAG family molecular chaperone regulator 3; BAG-3; Bcl-2-binding protein Bis; bcl-2-associated athanogene 3; Bcl-2-interacting death suppressor |
| UniProt Protein Name: | BAG family molecular chaperone regulator 3 |
| UniProt Synonym Protein Names: | Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis |
| Protein Family: | BAG family molecular chaperone regulator |
| UniProt Gene Name: | Bag3 |
| UniProt Entry Name: | BAG3_MOUSE |
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