B3GALT2 Antibody (PACO05611)
- SKU:
- PACO05611
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | B3GALT2 Antibody (PACO05611) |
| Antibody SKU: | PACO05611 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:40000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human β -1,3-Gal-T2. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | B3GALT2; β-1; 3-galactosyltransferase 2; β-1,3-GalTase 2; β3Gal-T2; β3GalT2; UDP-galactose:2-acetamido-2-deoxy-D-glucose 3β-galactosyltransferase 2 |
| UniProt Protein Function: | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. |
| NCBI Summary: | This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43825 |
| NCBI GenInfo Identifier: | 61211698 |
| NCBI Gene ID: | 8707 |
| NCBI Accession: | O43825.1 |
| UniProt Secondary Accession: | O43825,Q9BZQ9, B2RAB1, |
| UniProt Related Accession: | O43825 |
| Molecular Weight: | 49,213 Da |
| NCBI Full Name: | Beta-1,3-galactosyltransferase 2 |
| NCBI Synonym Full Names: | beta-1,3-galactosyltransferase 2 |
| NCBI Official Symbol: | B3GALT2 |
| NCBI Official Synonym Symbols: | GLCT2; BETA3GALT2; beta3Gal-T2 |
| NCBI Protein Information: | beta-1,3-galactosyltransferase 2 |
| UniProt Protein Name: | Beta-1,3-galactosyltransferase 2 |
| UniProt Synonym Protein Names: | UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2 |
| Protein Family: | Beta-1,3-galactosyltransferase |
| UniProt Gene Name: | B3GALT2 |
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