AWAT1 Antibody (PACO07132)
- SKU:
- PACO07132
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AWAT1 Antibody (PACO07132) |
| Antibody SKU: | PACO07132 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human DGAT2L3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of 293T NIH-3T3 COLO cells using DGAT2L3 Polyclonal Antibody. |
 | Western blot analysis of mouse-kidney KB lysis using DGAT2L3 antibody. |
 | Western Blot analysis of 293 cells using DGAT2L3 Polyclonal Antibody. |
| Synonyms: | AWAT1; DGA2; DGAT2L3; Acyl-CoA wax alcohol acyltransferase 1; Diacylglycerol O-acyltransferase 2-like protein 3; Diacylglycerol acyltransferase 2; Long-chain-alcohol O-fatty-acyltransferase 1 |
| UniProt Protein Function: | DGAT2L3: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20). Belongs to the diacylglycerol acyltransferase family.Protein type: EC 2.3.1.75; Membrane protein, integral; Membrane protein, multi-pass; TransferaseChromosomal Location of Human Ortholog: Xq13.1Cellular Component: endoplasmic reticulum membraneMolecular Function: long-chain-alcohol O-fatty-acyltransferase activityBiological Process: arachidonic acid metabolic process; wax biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the diacylglycerol acyltransferase family. It esterifies long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that this enzyme plays a central role in lipid metabolism in skin. Consistent with this observation, this protein is predominantly expressed in the sebaceous gland of the skin. [provided by RefSeq, Sep 2009] |
| UniProt Code: | Q58HT5 |
| NCBI GenInfo Identifier: | 61888902 |
| NCBI Gene ID: | 158833 |
| NCBI Accession: | NP_001013597.1 |
| UniProt Secondary Accession: | Q58HT5,Q5JT21, Q6IEE4 |
| UniProt Related Accession: | Q58HT5 |
| Molecular Weight: | 37,759 Da |
| NCBI Full Name: | acyl-CoA wax alcohol acyltransferase 1 |
| NCBI Synonym Full Names: | acyl-CoA wax alcohol acyltransferase 1 |
| NCBI Official Symbol: | AWAT1 |
| NCBI Official Synonym Symbols: | DGA2; DGAT2L3 |
| NCBI Protein Information: | acyl-CoA wax alcohol acyltransferase 1 |
| UniProt Protein Name: | Acyl-CoA wax alcohol acyltransferase 1 |
| UniProt Synonym Protein Names: | Diacylglycerol O-acyltransferase 2-like protein 3; Diacylglycerol acyltransferase 2; Long-chain-alcohol O-fatty-acyltransferase 1 |
| Protein Family: | Acyl-CoA wax alcohol acyltransferase |
| UniProt Gene Name: | AWAT1 |
| UniProt Entry Name: |
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