Description
Antibody Name: | AVPR1B Antibody (PACO07400) |
Antibody SKU: | PACO07400 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:10000-1:20000, IHC-p:1:50-1:300 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide from human protein at AA range: 271-320 |
Form: | Liquid |
Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200. |
Synonyms: | Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor) |
UniProt Protein Function: | AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 1q32 Cellular Component: endosome; integral to plasma membrane; plasma membrane Molecular Function:peptide binding; protein kinase C binding Biological Process: cellular response to hormone stimulus; elevation of cytosolic calcium ion concentration; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin |
NCBI Summary: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008] |
UniProt Code: | P47901 |
NCBI GenInfo Identifier: | 1351392 |
NCBI Gene ID: | 553 |
NCBI Accession: | P47901.1 |
UniProt Secondary Accession: | P47901,Q5TZ00, B0M0J6, |
UniProt Related Accession: | P47901 |
Molecular Weight: | 46,971 Da |
NCBI Full Name: | Vasopressin V1b receptor |
NCBI Synonym Full Names: | arginine vasopressin receptor 1B |
NCBI Official Symbol: | AVPR1B |
NCBI Official Synonym Symbols: | AVPR3 |
NCBI Protein Information: | vasopressin V1b receptor |
UniProt Protein Name: | Vasopressin V1b receptor |
UniProt Synonym Protein Names: | AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
Protein Family: | Vasopressin V1b receptor |
UniProt Gene Name: | AVPR1B |
UniProt Entry Name: | V1BR_HUMAN |
Antibodies | ELISA Kits |
AVPR1B Antibody (PACO00448) | Human AVPR1b / Vasopressin V1b receptor ELISA Kit |
Human Vasopressin V1b receptor (AVPR1B) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |