AVPR1B Antibody (PACO00448)
- SKU:
- PACO00448
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AVPR1B Antibody |
| Antibody SKU: | PACO00448 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human AVP Receptor V3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| UniProt Protein Function: | AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 1q32 Cellular Component: endosome; integral to plasma membrane; plasma membrane Molecular Function:peptide binding; protein kinase C binding Biological Process: cellular response to hormone stimulus; elevation of cytosolic calcium ion concentration; phospholipase C activation; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin |
| NCBI Summary: | The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47901 |
| NCBI GenInfo Identifier: | 1351392 |
| NCBI Gene ID: | 553 |
| NCBI Accession: | P47901.1 |
| UniProt Secondary Accession: | P47901,Q5TZ00, B0M0J6, |
| UniProt Related Accession: | P47901 |
| Molecular Weight: | 46,971 Da |
| NCBI Full Name: | Vasopressin V1b receptor |
| NCBI Synonym Full Names: | arginine vasopressin receptor 1B |
| NCBI Official Symbol: | AVPR1B |
| NCBI Official Synonym Symbols: | AVPR3 |
| NCBI Protein Information: | vasopressin V1b receptor |
| UniProt Protein Name: | Vasopressin V1b receptor |
| UniProt Synonym Protein Names: | AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor |
| Protein Family: | Vasopressin V1b receptor |
| UniProt Gene Name: | AVPR1B |
| UniProt Entry Name: | V1BR_HUMAN |
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