Name: Avpr1a Antibody (PACO33632)
SKU: PACO33632
Availability: OutOfStock

Antibody Name:	Avpr1a Antibody (PACO33632)
Antibody SKU:	PACO33632
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200
Species Reactivity:	Rat, Mouse
Immunogen:	Recombinant Rat Vasopressin V1a receptor protein (7-52AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot All lanes: Avpr1a antibody at 2µg/ml + Mouse spleen tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48 kDa Observed band size: 48 kDa .
	Immunohistochemistry of paraffin-embedded human colon cancer using PACO33632 at dilution of 1:100.

Background:	Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.
Synonyms:	Vasopressin V1a receptor (V1aR) (AVPR V1a) (Antidiuretic hormone receptor 1a) (Vascular/hepatic-type arginine vasopressin receptor), Avpr1a

UniProt Protein Function:	AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
UniProt Protein Details:	Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1 Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; integral to membrane; plasma membrane; cytoplasmic vesicle Molecular Function:V1A vasopressin receptor binding; peptide hormone binding; vasopressin receptor activity Biological Process: positive regulation of glutamate secretion; positive regulation of cellular pH reduction; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; positive regulation of glycogen catabolic process; response to organic substance; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; response to inorganic substance; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; regulation of adrenocorticotropin hormone secretion; positive regulation of vasoconstriction; sperm ejaculation; positive regulation of blood pressure
NCBI Summary:	This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues. [provided by RefSeq, Jul 2008]
UniProt Code:	P30560
NCBI GenInfo Identifier:	108935913
NCBI Gene ID:	25107
NCBI Accession:	P30560.4
UniProt Secondary Accession:	P30560,Q5M8D1, Q62874, Q9QW18,
UniProt Related Accession:	P30560
Molecular Weight:	47,655 Da
NCBI Full Name:	Vasopressin V1a receptor
NCBI Synonym Full Names:	arginine vasopressin receptor 1A
NCBI Official Symbol:	Avpr1a
NCBI Official Synonym Symbols:	V1a; AVPR; V1aR
NCBI Protein Information:	vasopressin V1a receptor; antidiuretic hormone receptor 1a; arginine vasopressin receptor V1a; vascular/hepatic-type arginine vasopressin receptor
UniProt Protein Name:	Vasopressin V1a receptor
UniProt Synonym Protein Names:	AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
Protein Family:	Vasopressin V1a receptor
UniProt Gene Name:	Avpr1a
UniProt Entry Name:	V1AR_RAT