ATP6AP1 Monoclonal Antibody
- SKU:
- CAB22468
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | ATP6AP1 Monoclonal Antibody |
| Product Code: | CAB22468 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57179 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse kidney |
| Cellular Location: | Single-pass membrane protein, Vacuole membrane |
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATP6AP1 (NP_001174.2). |
| Sequence: | MMAAM ATARV RMGPR CAQAL WRMPW LPVFL SLAAA AAAAA AEQQV PLVLW SSDRD LWAPA ADTHE GHITS DLQLS TYLDP ALELG PRNVL LFLQD KLSIE |
| Synonyms: | 16A, CF2, Ac45, XAP3, XAP-3, ATP6S1, VATPS1, ATP6IP1 |
| Calculated MW: | 52kDa |
| Observed MW: | 65kDa |
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