Description
Antibody Name: | ATP2C2 Antibody (PACO62239) |
Antibody SKU: | PACO62239 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Calcium-transporting ATPase type 2C member 2 protein (621-702AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of A549 cells with PACO62239 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. |
Synonyms: | Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 3.6.3.8) (Secretory pathway Ca(2+)-ATPase 2), ATP2C2, KIAA0703 SPCA2 |
UniProt Protein Function: | ATP2C2: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.6.3.8; Membrane protein, integral; Hydrolase; Transporter; Transporter, ion channel; Membrane protein, multi-passChromosomal Location of Human Ortholog: 16q24.1Cellular Component: Golgi membrane; integral to membraneMolecular Function: protein binding; calcium-transporting ATPase activity; metal ion binding; ATP bindingBiological Process: metabolic process; transmembrane transport |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O75185 |
NCBI GenInfo Identifier: | 612339337 |
NCBI Gene ID: | 9914 |
NCBI Accession: | NP_055676 |
UniProt Secondary Accession: | O75185 |
UniProt Related Accession: | O75185 |
Molecular Weight: | |
NCBI Full Name: | calcium-transporting ATPase type 2C member 2 isoform 2 |
NCBI Synonym Full Names: | ATPase secretory pathway Ca2+ transporting 2 |
NCBI Official Symbol: | ATP2C2 |
NCBI Official Synonym Symbols: | SPCA2 |
NCBI Protein Information: | calcium-transporting ATPase type 2C member 2 |
UniProt Protein Name: | Calcium-transporting ATPase type 2C member 2 |
UniProt Synonym Protein Names: | Secretory pathway Ca(2+)-ATPase 2 |
Protein Family: | |
UniProt Gene Name: | ATP2C2 |
UniProt Entry Name: | AT2C2_HUMAN |