ATP2B1 Monoclonal Antibody
- SKU:
- CAB24346
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | ATP2B1 Monoclonal Antibody |
| Product Code: | CAB24346 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61750 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1(Low expression control), A549, Neuro-2a, Rat lung |
| Cellular Location: | Cell membrane |
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 5-103 of human ATP2B1 (NP_001673.2). |
| Sequence: | ANNSV AYSGV KNSLK EANHD GDFGI TLAEL RALME LRSTD ALRKI QESYG DVYGI CTKLK TSPNE GLSGN PADLE RREAV FGKNF IPPKK PKTFL QLVW |
| Synonyms: | MRD66, PMCA1, PMCA1kb, |
| Calculated MW: | 135kDa |
| Observed MW: | 135-180kDa |
Related Products
IκBα Monoclonal Antibody
Chk1 Monoclonal Antibody
HN1 Monoclonal Antibody
