Description
Product Name: | ATP1A4 Monoclonal Antibody |
Product Code: | CAB23196 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59773 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | bewo, MCF7, Mouse brain |
Cellular Location: | Cell membrane, Multi-pass membrane protein |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 401-530 of human ATP1A4 (NP_653300.2) |
Sequence: | FDMTV YEADT TEEQT GKTFT KSSDT WFMLA RIAGL CNRAD FKANQ EILPI AKRAT TGDAS ESALL KFIEQ SYSSV AEMRE KNPKV AEIPF NSTNK YQMSI HLRED SSQTH VLMMK GAPER ILEFC STFLL |
Synonyms: | ATP1A1, ATP1AL2 |
Calculated MW: | 19KDa/114KDa |
Observed MW: | 113kDa |