Name: Atp1a1 (Ab-23) Antibody (PACO23621)
SKU: PACO23621
Availability: OutOfStock

Antibody Name:	Atp1a1 (Ab-23) Antibody (PACO23621)
Antibody SKU:	PACO23621
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500
Species Reactivity:	Human, Rat
Immunogen:	Synthesized non-phosphopeptide derived from human ATP1 alpha 1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunofluorescence analysis of HeLa cells, using ATP1alpha 1/Na+K+ ATPase1 (Ab-23) antibody.
	Western blot analysis of extracts from K562 cells (Lane 2), using ATP1 alpha 1/Na+K+ ATPase1 (Ab-23) antiobdy. The lane on the left is treated with synthesized peptide.
	Western blot analysis of extracts from HeLa cells, using ATP1 alpha 1/Na+K+ ATPase1 (Ab-23) antibody.

Background:	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Synonyms:	A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide

UniProt Protein Function:	This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
UniProt Protein Details:
NCBI Summary:	mediates Na+ and K+ transport; may play a role in regulation of blood pressure [RGD, Feb 2006]
UniProt Code:	P06685
NCBI GenInfo Identifier:	114376
NCBI Gene ID:	24211
NCBI Accession:	P06685.1
UniProt Secondary Accession:	P06685,Q64609
UniProt Related Accession:	P06685
Molecular Weight:	113,054 Da
NCBI Full Name:	Sodium/potassium-transporting ATPase subunit alpha-1
NCBI Synonym Full Names:	ATPase Na+/K+ transporting subunit alpha 1
NCBI Official Symbol:	Atp1a1
NCBI Official Synonym Symbols:	Nkaa1b
NCBI Protein Information:	sodium/potassium-transporting ATPase subunit alpha-1
UniProt Protein Name:	Sodium/potassium-transporting ATPase subunit alpha-1
UniProt Synonym Protein Names:	Sodium pump subunit alpha-1
Protein Family:	Sodium/potassium-transporting ATPase
UniProt Gene Name:	Atp1a1
UniProt Entry Name:	AT1A1_RAT