Description
Product Name: | ATG7 Monoclonal Antibody |
Product Code: | CAB21895 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC2631 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IP 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HepG2 |
Cellular Location: | Cytoplasm, Preautophagosomal structure |
Customer Validation: | WB(Actinopterygii) |
This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-703 of human ATG7 (O95352). |
Sequence: | GGYAI ASSSD DRMNE PPTSL GLVPH QIRGF LSRFD NVLPV SLAFD KCTAC SSKVL DQYER EGFNF LAKVF NSSHS FLEDL TGLTL LHQET QAAEI WDMSD DETI |
Synonyms: | GSA7, APG7L, SCAR31, APG7-LIKE |
Calculated MW: | 78kDa |
Observed MW: | 75kDa |