ATG4B Polyclonal Antibody
- SKU:
- CAB21409
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | ATG4B Polyclonal Antibody |
| Product Code: | CAB21409 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human ATG4B (NP_037457.3). |
| Sequence: | MDAAT LTYDT LRFAE FEDFP ETSEP VWILG RKYSI FTEKD EILSD VASRL WFTYR KNFPA IGGTG PTSDT GWGCM LRCGQ MIFAQ ALVCR HLGRD WRWTQ RKRQP DSYFS VLNAF IDRKD SYYSI HQIAQ MGVGE GKSIG QWYGP NTVAQ VLKKL AVFDT WSSLA VHIAM DNTVV MEEIR RLCRT SVPCA GATAF PADSD RHCNG FPAGA EVTNR PSPWR PLVLL IPLRL GLTDI NEAYV ETLKH CFMMP QSLGV IGGKP NSAHY FIGYV GEELI YLDPH TTQPA VEPTD GCFIP DESFH CQHPP CRMSI AELDP SIAVG FFCKT EDDFN DWCQQ VKKLS LLGGA LPMFE LVELQ PSHLA CPDVL NLSLD SSDVE RLERF FDSED EDFEI LSL |
| Synonyms: | APG4B, AUTL1, HsAPG4B |
| Calculated MW: | 44kDa |
| Observed MW: | Refer to figures |
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