ATG16L1 Polyclonal Antibody (CAB21763)
- SKU:
- CAB21763
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | ATG16L1 Polyclonal Antibody |
| Product Code: | CAB21763 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Mouse thymus, Rat thymus |
| Cellular Location: | Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane |
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ATG16L1 (NP_110430.5). |
| Sequence: | KHDVP NRHEI SPGHD GTWND NQLQE MAQLR IKHQE ELTEL HKKRG ELAQL VIDLN NQMQR KDREM QMNEA KIAEC LQTIS DLETE CLDLR TKLCD LERAN QTLKD EYDAL QITFT ALEGK LRKTT EENQE LVTRW MAEKA QEANR LNAEN EKDSR RRQAR LQKEL AEAAK EPLPV EQDDD IEVIV DETSD HTEET SPVRA ISRAA TKRLS QPAGG LLDSI TNIFG RRSVS SFPVP QDNVD T |
| Synonyms: | IBD10, WDR30, APG16L, ATG16A, ATG16L |
| Calculated MW: | 68kDa |
| Observed MW: | 66kDa/68kDa |
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