ATG12 Monoclonal Antibody

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SKU:
CAB22788
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC
Applications:
IP

Description

Product Name:ATG12 Monoclonal Antibody
Product Code:CAB22788
Reactivity:Human, Mouse
Applications:Western blotting, Immunohistochemistry, Immunoprecipitation
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC2663
Reactivity:Human, Mouse
Tested Applications:WB, IHC-P, IP, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunoprecipitation
Recommended Dilution:WB 1:500-1:1000, IHC-P 1:50-1:200, IP 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HCT 116, 293T
Cellular Location:Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATG12 (NP_004698.3).
Sequence:MAEEP QSVLQ LPTSI AAGGE GLTDV SPETT TPEPP SSAAV SPGTE EPAGD TKKKI DILLK AVGDT PIMKT KKWAV ERTRT IQGLI DFIKK FLKLV ASEQL
Synonyms:APG12, FBR93, APG12L, HAPG12
Calculated MW:15kDa
Observed MW:55kDa
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