ATG12 Monoclonal Antibody
- SKU:
- CAB22788
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IP
Description
| Product Name: | ATG12 Monoclonal Antibody |
| Product Code: | CAB22788 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2663 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IP 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HCT 116, 293T |
| Cellular Location: | Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane |
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATG12 (NP_004698.3). |
| Sequence: | MAEEP QSVLQ LPTSI AAGGE GLTDV SPETT TPEPP SSAAV SPGTE EPAGD TKKKI DILLK AVGDT PIMKT KKWAV ERTRT IQGLI DFIKK FLKLV ASEQL |
| Synonyms: | APG12, FBR93, APG12L, HAPG12 |
| Calculated MW: | 15kDa |
| Observed MW: | 55kDa |
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