ATG1 Antibody (PACO36678)
- SKU:
- PACO36678
- Product Type:
- Antibody
- Reactivity:
- Fungus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ATG1 Antibody (PACO36678) |
| Antibody SKU: | PACO36678 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Candida glabrata |
| Immunogen: | Recombinant Candida glabrata Serine/threonine-protein kinase ATG1 protein (11-312AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. |
| Synonyms: | Serine/threonine-protein kinase ATG1 (EC 2.7.11.1) (Autophagy-related protein 1), ATG1 |
| UniProt Protein Function: | Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates. Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6FL58 |
| NCBI GenInfo Identifier: | 50293249 |
| NCBI Gene ID: | 2890744 |
| NCBI Accession: | XP_449036.1 |
| UniProt Secondary Accession: | Q6FL58 |
| UniProt Related Accession: | Q6FL58 |
| Molecular Weight: | 107,095 Da |
| NCBI Full Name: | hypothetical protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | CAGL0L06006g |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | hypothetical protein |
| UniProt Protein Name: | Serine/threonine-protein kinase ATG1 |
| UniProt Synonym Protein Names: | Autophagy-related protein 1 |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | ATG1 |
| UniProt Entry Name: | ATG1_CANGA |
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