ATAD5 Antibody (PACO19327)
- SKU:
- PACO19327
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ATAD5 Antibody (PACO19327) |
| Antibody SKU: | PACO19327 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human ATAD5 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A431 cells, Primary antibody: PACO19327(ATAD5 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds. |
| Background: | ATAD5 (ATPase family, AAA domain containing 5), also known as chromosome fragility-associated gene 1 protein, FRAG1 or ELG1, is a 1,844 amino acid, nuclear protein that is involved in the DNA damage response and belongs to the AAA ATPase family. Existing as two alternatively spliced isoforms, ATAD5 interacts with Rad9 in growing cells where it assists in interactions between Rad9 and Bcl-2. |
| Synonyms: | ATPase family, AAA domain containing 5 |
| UniProt Protein Function: | ATAD5: Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 17q11.2Cellular Component: nucleusMolecular Function: ATP bindingBiological Process: response to DNA damage stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96QE3 |
| NCBI GenInfo Identifier: | 26080431 |
| NCBI Gene ID: | 79915 |
| NCBI Accession: | NP_079133.3 |
| UniProt Secondary Accession: | Q96QE3,Q05DH0, Q69YR6, Q9H9I1 |
| UniProt Related Accession: | Q96QE3 |
| Molecular Weight: | 135,878 Da |
| NCBI Full Name: | ATPase family AAA domain-containing protein 5 |
| NCBI Synonym Full Names: | ATPase family, AAA domain containing 5 |
| NCBI Official Symbol: | ATAD5 |
| NCBI Official Synonym Symbols: | ELG1; FRAG1; C17orf41 |
| NCBI Protein Information: | ATPase family AAA domain-containing protein 5; chromosome fragility associated gene 1; chromosome fragility-associated gene 1 protein; enhanced level of genomic instability 1 homolog |
| UniProt Protein Name: | ATPase family AAA domain-containing protein 5 |
| UniProt Synonym Protein Names: | Chromosome fragility-associated gene 1 protein |
| Protein Family: | ATPase family AAA domain-containing protein |
| UniProt Gene Name: | ATAD5 |
| UniProt Entry Name: | ATAD5_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli