ASCL2 Antibody (PACO21935)
- SKU:
- PACO21935
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ASCL2 Antibody (PACO21935) |
| Antibody SKU: | PACO21935 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from Internal of human ASCL2. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from K562 cells, using ASCL2 antibody. |
| Background: | AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Westerman B.A., Placenta 22:511-518(2001). |
| Synonyms: | achaete-scute complex homolog 2 (Drosophila); achaete-scute complex-like 2; Achaete-scute homolog 2; ASCL2; ASH-2 |
| UniProt Protein Function: | ASCL2: a basic helix-loop-helix transcription factor, plays an essential role in the maintenance of adult intestinal stem cellsProtein type: DNA-bindingChromosomal Location of Human Ortholog: 11p15.5Cellular Component: cytoplasm; nucleusBiological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of neurogenesis; response to hypoxia; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99929 |
| NCBI GenInfo Identifier: | 12644476 |
| NCBI Gene ID: | 430 |
| NCBI Accession: | Q99929.2 |
| UniProt Secondary Accession: | Q99929,Q6PEY9, Q9UM68 |
| UniProt Related Accession: | Q99929 |
| Molecular Weight: | 20,185 Da |
| NCBI Full Name: | Achaete-scute homolog 2 |
| NCBI Synonym Full Names: | achaete-scute family bHLH transcription factor 2 |
| NCBI Official Symbol: | ASCL2 |
| NCBI Official Synonym Symbols: | ASH2; HASH2; MASH2; bHLHa45 |
| NCBI Protein Information: | achaete-scute homolog 2 |
| UniProt Protein Name: | Achaete-scute homolog 2 |
| UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 45; bHLHa45; Mash2 |
| Protein Family: | Achaete-scute |
| UniProt Gene Name: | ASCL2 |
| UniProt Entry Name: | ASCL2_HUMAN |
| Antibodies |
| ASCL2 Antibody (PACO04341) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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